5TCU

Methicillin sensitive Staphylococcus aureus 70S ribosome

This is a large structure.

Summary for 5TCU

EMDB information8369 8402
Descriptor16S RRNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ... (54 entities in total)
Functional Keywords70s ribosome, cryoem, ribosome, staphylococcus aureus, ribosome-antibiotic complex, ribosome/antibiotic
Biological sourceStaphylococcus aureus (strain NCTC 8325)
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Total number of polymer chains52
Total molecular weight2119582.33
Authors
Eyal, Z.,Ahmed, T.,Belousoff, N.,Mishra, S.,Matzov, D.,Bashan, A.,Zimmerman, E.,Lithgow, T.,Bhushan, S.,Yonath, A. (deposition date: 2016-09-15, release date: 2017-05-24, Last modification date: 2019-12-18)
Primary citation
Belousoff, M.J.,Eyal, Z.,Radjainia, M.,Ahmed, T.,Bamert, R.S.,Matzov, D.,Bashan, A.,Zimmerman, E.,Mishra, S.,Cameron, D.,Elmlund, H.,Peleg, A.Y.,Bhushan, S.,Lithgow, T.,Yonath, A.
Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
MBio, 8:-, 2017
PubMed: 28487427 (PDB entries with the same primary citation)
DOI: 10.1128/mBio.00395-17
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone6 0.2% 2.1% 0.39MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report