5T7V

Methicillin Resistant, Linezolid resistant Staphylococcus aureus 70S ribosome (delta S145 uL3)

This is a large structure.

Summary for 5T7V

EMDB information8369
Descriptor16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (43 entities in total)
Functional Keywords70s ribosome, methicillin resistant, linezolid resistant, cryoem, ribosome
Biological sourceStaphylococcus aureus
Total number of polymer chains42
Total molecular weight1971153.05
Authors
Belousoff, M.J.,Lithgow, T.,Eyal, Z.,Yonath, A.,Radjainia, M. (deposition date: 2016-09-06, release date: 2017-05-31, Last modification date: 2019-12-11)
Primary citation
Belousoff, M.J.,Eyal, Z.,Radjainia, M.,Ahmed, T.,Bamert, R.S.,Matzov, D.,Bashan, A.,Zimmerman, E.,Mishra, S.,Cameron, D.,Elmlund, H.,Peleg, A.Y.,Bhushan, S.,Lithgow, T.,Yonath, A.
Structural Basis for Linezolid Binding Site Rearrangement in theStaphylococcus aureusRibosome.
MBio, 8:-, 2017
PubMed: 28487427 (PDB entries with the same primary citation)
DOI: 10.1128/mBio.00395-17
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone4 0.1% 0.7% 0.36MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report