5JVH

The crystal structure large ribosomal subunit (50S) of Deinococcus radiodurans in complex with evernimicin

Summary for 5JVH

Descriptor23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... (30 entities in total)
Functional Keywordsribosome, antibiotics
Biological sourceDeinococcus radiodurans R1
Total number of polymer chains28
Total molecular weight1349716.82
Authors
Yonath, A. (deposition date: 2016-05-11, release date: 2016-11-09)
Primary citation
Krupkin, M.,Wekselman, I.,Matzov, D.,Eyal, Z.,Diskin Posner, Y.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A.
Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113:E6796-E6805, 2016
PubMed: 27791159 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1614297113
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.58 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.247171.2%17.6%3.0%0.46MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report