5JVG

The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin

Summary for 5JVG

Descriptor23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... (33 entities in total)
Functional Keywordsdeinococcus radiodurans, avilamycin, degradable antibiotics, ribosome, large ribosomal subunit, resistance
Biological sourceDeinococcus radiodurans R1
More
Total number of polymer chains29
Total molecular weight1372760.85
Authors
Krupkin, M.,Wekselman, I.,Matzov, D.,Eyal, Z.,Diskin Posner, Y.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A. (deposition date: 2016-05-11, release date: 2016-11-09, Last modification date: 2019-09-25)
Primary citation
Krupkin, M.,Wekselman, I.,Matzov, D.,Eyal, Z.,Diskin Posner, Y.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A.
Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113:E6796-E6805, 2016
PubMed: 27791159 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1614297113
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.428 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.25514 1.2% 15.5% 4.7% 0.49MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report