4WFN

Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 in complex with erythromycin

Summary for 4WFN

Related4U67
Descriptor50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ... (30 entities in total)
Functional Keywordsribosome, antibiotics, rresistance, erythromycin
Biological sourceDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
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Total number of polymer chains28
Total molecular weight1348061.6
Authors
Wekselman, I.,Zimmerman, E.,Rozenberg, H.,Bashan, A.,Yonath, A. (deposition date: 2014-09-16, release date: 2015-12-23, Last modification date: 2017-08-16)
Primary citation
Wekselman, I.,Zimmerman, E.,Davidovich, C.,Belousoff, M.,Matzov, D.,Krupkin, M.,Rozenberg, H.,Bashan, A.,Friedlander, G.,Kjeldgaard, J.,Ingmer, H.,Lindahl, L.,Zengel, J.M.,Yonath, A.
The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25:1233-1241.e3, 2017
PubMed: 28689968 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2017.06.004
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.54 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.284191.1%18.0%3.4%0.45MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report