Crystal structure of the N terminal domain of human Galectin 8

Summary for 4BMB

DescriptorGALECTIN-8, ZINC ION, BETA-LACTOSE, ... (6 entities in total)
Functional Keywordssugar binding protein, carbohydrate recognition
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm (Probable) O00214
Total number of polymer chains1
Total molecular weight17515.35
Buzamet, E.,Ruiz, F.M.,Menendez, M.,Romero, A.,Gabius, H.J.,Solis, D. (deposition date: 2013-05-07, release date: 2014-03-19)
Primary citation
Ruiz, F.M.,Scholz, B.A.,Buzamet, E.,Kopitz, J.,Andre, S.,Menendez, M.,Romero, A.,Solis, D.,Gabius, H.J.
Natural Single Amino Acid Polymorphism (F19Y) in Human Galectin-8: Detection of Structural Alterations and Increased Growth-Regulatory Activity on Tumor Cells.
FEBS J., 281:1446-, 2014
PubMed: 24418318 (PDB entries with the same primary citation)
DOI: 10.1111/FEBS.12716
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.180100.8%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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