3VUH

Crystal structure of a cysteine-deficient mutant M3 in MAP kinase JNK1

Summary for 3VUH

Related3VUD 3VUG 3VUI 3VUK 3VUL 3VUM
DescriptorMitogen-activated protein kinase 8, Peptide from C-Jun-amino-terminal kinase-interacting protein 1, SULFATE ION, ... (5 entities in total)
Functional Keywordstranscription, phosphorylation, atp binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight44571.13
Authors
Nakaniwa, T.,Kinoshita, T.,Inoue, T. (deposition date: 2012-06-28, release date: 2013-02-13, Last modification date: 2019-12-04)
Primary citation
Nakaniwa, T.,Fukada, H.,Inoue, T.,Gouda, M.,Nakai, R.,Kirii, Y.,Adachi, M.,Tamada, T.,Segawa, S.,Kuroki, R.,Tada, T.,Kinoshita, T.
Seven cysteine-deficient mutants depict the interplay between thermal and chemical stabilities of individual cysteine residues in mitogen-activated protein kinase c-Jun N-terminal kinase 1
Biochemistry, 51:8410-8421, 2012
PubMed: 23020677 (PDB entries with the same primary citation)
DOI: 10.1021/bi300918w
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25819 2.5% 10.8% 3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report