3MR3

Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1)

Summary for 3MR3

Related3MR2 3MR4 3MR5 3MR6
DescriptorDNA polymerase eta, DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total)
Functional Keywordspol eta, polymerase, thymine dimer, cpd, xpv, xeroderma pigmentosum variant, dna damage, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q9Y253
Total number of polymer chains3
Total molecular weight56552.47
Authors
Biertumpfel, C.,Zhao, Y.,Ramon-Maiques, S.,Gregory, M.T.,Lee, J.Y.,Yang, W. (deposition date: 2010-04-28, release date: 2010-06-30, Last modification date: 2012-03-21)
Primary citation
Biertumpfel, C.,Zhao, Y.,Kondo, Y.,Ramon-Maiques, S.,Gregory, M.,Lee, J.Y.,Masutani, C.,Lehmann, A.R.,Hanaoka, F.,Yang, W.
Structure and mechanism of human DNA polymerase eta.
Nature, 465:1044-1048, 2010
PubMed: 20577208 (PDB entries with the same primary citation)
DOI: 10.1038/nature09196
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.201210.2%2.8%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload