3J7O

Structure of the mammalian 60S ribosomal subunit

This is a large structure.
Replaces:  3J71

Summary for 3J7O

Related3J7P 3J7Q 3J7R
Integrates4W1Z 4W20
EMDB information2649
Descriptor28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... (47 entities in total)
Functional Keywordsmammalian, ribosome
Biological sourceSus scrofa (pig)
Total number of polymer chains45
Total molecular weight2090573.46
Authors
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.W.,Hegde, R.S. (deposition date: 2014-08-01, release date: 2014-09-03, Last modification date: 2018-07-18)
Primary citation
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.,Hegde, R.S.
Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157:1632-1643, 2014
PubMed: 24930395 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2014.05.024
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (3.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone574.2%21.9%0.28MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report