3AHQ

hyperactive human Ero1

Summary for 3AHQ

Related1RP4 3AHR
DescriptorERO1-like protein alpha, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywordsdisulfide bond, pdi, redox, hyperactive human ero1, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationEndoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side Q96HE7
Total number of polymer chains1
Total molecular weight54958.38
Authors
Inaba, K.,Sitia, R.,Suzuki, M. (deposition date: 2010-04-26, release date: 2010-12-22, Last modification date: 2011-07-13)
Primary citation
Inaba, K.,Masui, S.,Iida, H.,Vavassori, S.,Sitia, R.,Suzuki, M.
Crystal structures of human Ero1-alpha reveal the mechanisms of regulated and targeted oxidation of PDI
Embo J., 29:3330-3343, 2010
PubMed: 20834232 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2010.222
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27660.3%5.6%12.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report