Mine: Updated entries

6ZQT
  • Download 6zqt
  • View 6zqt
Molmil generated image of 6zqt
CRYSTAL STRUCTURE OF THE RLIP76 RAL BINDING DOMAIN MUTANT (E427H/Q433L/K440R) IN COMPLEX WITH RALB-GMPPNP
Descriptor:Ras-related protein Ral-B, RalA-binding protein 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Hurd, C., Brear, P., Revell, J., Ross, S., Mott, H., Owen, D.
Deposit date:2020-07-10
Release date:2020-11-25
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.
J.Biol.Chem., 2020
6ZRN
  • Download 6zrn
  • View 6zrn
Molmil generated image of 6zrn
CRYSTAL STRUCTURE OF THE RLIP76 RAL BINDING DOMAIN MUTANT (E427S/L429M/Q433L/K440R) IN COMPLEX WITH RALB-GMPPNP
Descriptor:Ras-related protein Ral-B, RalA-binding protein 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Hurd, C., Brear, P., Revell, J., Ross, S., Mott, H., Owen, D.
Deposit date:2020-07-13
Release date:2020-11-25
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.
J.Biol.Chem., 2020
6ZU4
  • Download 6zu4
  • View 6zu4
Molmil generated image of 6zu4
HUMAN SIRT6 13-308 IN COMPLEX WITH ADP-RIBOSE AND THE ACTIVATOR FLUVASTATIN
Descriptor:NAD-dependent protein deacetylase sirtuin-6, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ZINC ION, ...
Authors:You, W., Steegborn, C.
Deposit date:2020-07-21
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural Basis for Activation of Human Sirtuin 6 by Fluvastatin.
Acs Med.Chem.Lett., 11, 2020
6ZV9
  • Download 6zv9
  • View 6zv9
Molmil generated image of 6zv9
TERBIUM(III)-BOUND DE NOVO TIM BARREL-FERREDOXIN FOLD FUSION DIMER WITH 4-GLUTAMATE BINDING SITE AND TRYPTOPHAN ANTENNA (TFD-EE N6W)
Descriptor:TFD-EE, TERBIUM(III) ION, 1,2-ETHANEDIOL
Authors:Caldwell, S., Haydon, I., Piperidou, N., Huang, P., Hilvert, D., Baker, D., Zeymer, C.
Deposit date:2020-07-24
Release date:2020-11-25
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion.
Proc.Natl.Acad.Sci.USA, 2020
6ZY2
  • Download 6zy2
  • View 6zy2
Molmil generated image of 6zy2
CRYO-EM STRUCTURE OF APO MLAFEDB
Descriptor:YrbD protein, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ...
Authors:Dong, C.J., Dong, H.H.
Deposit date:2020-07-30
Release date:2020-11-25
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 2020
6ZY3
  • Download 6zy3
  • View 6zy3
Molmil generated image of 6zy3
CRYO-EM STRUCTURE OF MLAFEDB IN COMPLEX WITH PHOSPHOLIPID
Descriptor:YrbD protein, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ...
Authors:Dong, C.J., Dong, H.H.
Deposit date:2020-07-30
Release date:2020-11-25
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 2020
6ZY4
  • Download 6zy4
  • View 6zy4
Molmil generated image of 6zy4
CRYO-EM STRUCTURE OF MLAFEDB IN COMPLEX WITH ADP
Descriptor:YrbD protein, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ...
Authors:Dong, C.J., Dong, H.H.
Deposit date:2020-07-30
Release date:2020-11-25
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 2020
6ZY9
  • Download 6zy9
  • View 6zy9
Molmil generated image of 6zy9
CRYO-EM STRUCTURE OF MLAFEDB IN COMPLEX WITH AMP-PNP
Descriptor:YrbD protein, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ...
Authors:Dong, C.J., Dong, H.H.
Deposit date:2020-07-30
Release date:2020-11-25
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 2020
7A5M
  • Download 7a5m
  • View 7a5m
Molmil generated image of 7a5m
ENAH EVH1 IN COMPLEX WITH AC-[2-CL-F]-[PROM-2]-[PROM-17]-OME
Descriptor:Protein enabled homolog, Ac-[2-Cl-F]-[ProM-2]-[ProM-17]-OMe, NITRATE ION
Authors:Barone, M., Roske, Y.
Deposit date:2020-08-21
Release date:2020-10-07
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (0.78 Å)
Cite:Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
7AD9
  • Download 7ad9
  • View 7ad9
Molmil generated image of 7ad9
STRUCTURE OF THE LIFEACT-F-ACTIN COMPLEX
Descriptor:Lifeact, Actin, alpha skeletal muscle, ...
Authors:Belyy, A., Merino, F., Sitsel, O., Raunser, S.
Deposit date:2020-09-14
Release date:2020-10-28
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Lifeact-F-actin complex.
Plos Biol., 18, 2020
7AHC
  • Download 7ahc
  • View 7ahc
Molmil generated image of 7ahc
OPUA APO INWARD-FACING
Descriptor:ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component
Authors:Sikkema, H.R., Rheinberger, J., Paulino, C., Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHD
  • Download 7ahd
  • View 7ahd
Molmil generated image of 7ahd
OPUA (E190Q) OCCLUDED
Descriptor:ABC-type proline/glycine betaine transport system ATPase component, ABC transporter permease subunit, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Sikkema, H.R., Rheinberger, J., Paulino, C., Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHE
  • Download 7ahe
  • View 7ahe
Molmil generated image of 7ahe
OPUA INHIBITED INWARD FACING
Descriptor:ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide
Authors:Sikkema, H.R., Rheinberger, J., Paulino, C., Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHH
  • Download 7ahh
  • View 7ahh
Molmil generated image of 7ahh
OPUA INHIBITED INWARD-FACING, SBD DOCKED
Descriptor:ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, TRIMETHYL GLYCINE, ...
Authors:Sikkema, H.R., Rheinberger, J., Paulino, C., Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHK
  • Download 7ahk
  • View 7ahk
Molmil generated image of 7ahk
CRYSTAL STRUCTURE OF THE OUTWARD-FACING STATE OF THE SUBSTRATE-FREE NA+-ONLY BOUND GLUTAMATE TRANSPORTER HOMOLOG GLTPH
Descriptor:Glutamate transporter homolog, SODIUM ION, octyl beta-D-glucopyranoside, ...
Authors:Kovalev, K., Alleva, C., Astashkin, A., Machtens, J.-P., Fahlke, C., Gordeliy, V.
Deposit date:2020-09-24
Release date:2020-11-18
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Na + -dependent gate dynamics and electrostatic attraction ensure substrate coupling in glutamate transporters.
Sci Adv, 6, 2020
7AKI
  • Download 7aki
  • View 7aki
Molmil generated image of 7aki
ENAH EVH1 IN COMPLEX WITH AC-[2-CL-F]-[PROM-2]-[PROM-1]-NH2
Descriptor:Protein enabled homolog, NITRATE ION, (3~{S},7~{R},10~{R},13~{S})-4-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxamide
Authors:Barone, M., Roske, Y.
Deposit date:2020-10-01
Release date:2020-11-25
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
7AKU
  • Download 7aku
  • View 7aku
Molmil generated image of 7aku
STRUCTURE OF SARS-COV-2 MAIN PROTEASE BOUND TO CALPEPTIN.
Descriptor:Replicase polyprotein 1ab, Calpeptin, CHLORIDE ION
Authors:Guenther, S., Reinke, P., Oberthuer, D., Yefanov, O., Gelisio, L., Ginn, H., Lieske, J., Domaracky, M., Brehm, W., Rahmani Mashour, A., White, T.A., Knoska, J., Pena Esperanza, G., Koua, F., Tolstikova, A., Groessler, M., Fischer, P., Hennicke, V., Fleckenstein, H., Trost, F., Galchenkova, M., Gevorkov, Y., Li, C., Awel, S., Paulraj, L.X., Ullah, N., Falke, S., Alves Franca, B., Schwinzer, M., Brognaro, H., Werner, N., Perbandt, M., Tidow, H., Seychell, B., Beck, T., Meier, S., Doyle, J.J., Giseler, H., Melo, D., Dunkel, I., Lane, T.J., Peck, A., Saouane, S., Hakanpaeae, J., Meyer, J., Noei, H., Gribbon, P., Ellinger, B., Kuzikov, M., Wolf, M., Zhang, L., Ehrt, C., Pletzer-Zelgert, J., Wollenhaupt, J., Feiler, C., Weiss, M., Schulz, E.C., Mehrabi, P., Norton-Baker, B., Schmidt, C., Lorenzen, K., Schubert, R., Han, H., Chari, A., Fernandez Garcia, Y., Turk, D., Hilgenfeld, R., Rarey, M., Zaliani, A., Chapman, H.N., Pearson, A., Betzel, C., Meents, A.
Deposit date:2020-10-02
Release date:2020-10-28
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Inhibition of SARS-CoV-2 main protease by allosteric drug-binding
Biorxiv, 2020
7BOV
  • Download 7bov
  • View 7bov
Molmil generated image of 7bov
THE STRUCTURE OF BACILLUS SUBTILIS GLYCOSYLTRANSFERASE,BS-YJIC
Descriptor:Uncharacterized UDP-glucosyltransferase YjiC, SODIUM ION, GLYCEROL
Authors:Zhao, C., Liu, B., Zhao, N.L., Luo, Y.Z., Bao, R.
Deposit date:2020-03-20
Release date:2020-05-13
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:Structural and biochemical studies of the glycosyltransferase Bs-YjiC from Bacillus subtilis.
Int.J.Biol.Macromol., 2020
7BP2
  • Download 7bp2
  • View 7bp2
Molmil generated image of 7bp2
STRUCTURAL MECHANISM DIRECTING NUCLEOSOME REORGANIZATION BY NAP1-RELATED PROTEIN 1 (NRP1)
Descriptor:Histone H2A.6, Histone H2B.1, SULFATE ION, ...
Authors:Luo, Q., Baihui, W.
Deposit date:2020-03-21
Release date:2020-11-11
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 2020
7BP4
  • Download 7bp4
  • View 7bp4
Molmil generated image of 7bp4
STRUCTURAL INSIGHTS INTO NUCLEOSOME REORGANIZATION BY NAP1-RELATED PROTEIN 1 (NRP1)
Descriptor:Histone H2A.6, Histone H2B.1, ASP-ASP-ASP-ASP-TYR, ...
Authors:Luo, Q., Baihui, W.
Deposit date:2020-03-21
Release date:2020-11-11
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 2020
7BP5
  • Download 7bp5
  • View 7bp5
Molmil generated image of 7bp5
STRUCTURAL INSIGHTS INTO NUCLEOSOME REORGANIZATION BY NAP1-RELATED PROTEIN 1 (NRP1)
Descriptor:Histone H2A.6, Histone H2B.1, ASN-ASP-PRO-ASP-TYR, ...
Authors:Luo, Q., Baihui, W.
Deposit date:2020-03-21
Release date:2020-11-11
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 2020
7BP6
  • Download 7bp6
  • View 7bp6
Molmil generated image of 7bp6
STRUCTURAL INSIGHTS INTO NUCLEOSOME REORGANIZATION BY NAP1-RELATED PROTEIN 1 (NRP1)
Descriptor:Histone H2A.6, Histone H2B.1, NRP1-CTAD
Authors:Luo, Q., Baihui, W.
Deposit date:2020-03-21
Release date:2020-11-11
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B.
Proc.Natl.Acad.Sci.USA, 2020
7BPY
  • Download 7bpy
  • View 7bpy
Molmil generated image of 7bpy
X-RAY STRUCTURE OF HUMAN PPARALPHA LIGAND BINDING DOMAIN-CLOFIBRIC ACID-SRC1 COACTIVATOR PEPTIDE CO-CRYSTALS OBTAINED BY DELIPIDATION AND CO-CRYSTALLIZATION
Descriptor:Peroxisome proliferator-activated receptor alpha, 15-meric peptide from Nuclear receptor coactivator 1, 2-(4-chloranylphenoxy)-2-methyl-propanoic acid
Authors:Kamata, S., Ishikawa, R., Akahane, M., Oyama, T., Ishii, I.
Deposit date:2020-03-23
Release date:2020-11-11
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
7BPZ
  • Download 7bpz
  • View 7bpz
Molmil generated image of 7bpz
X-RAY STRUCTURE OF HUMAN PPARALPHA LIGAND BINDING DOMAIN-BEZAFIBRATE-SRC1 COACTIVATOR PEPTIDE CO-CRYSTALS OBTAINED BY SOAKING
Descriptor:Peroxisome proliferator-activated receptor alpha, 15-meric peptide from Nuclear receptor coactivator 1, 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID
Authors:Kamata, S., Ishikawa, R., Akahane, M., Oyama, T., Ishii, I.
Deposit date:2020-03-23
Release date:2020-11-11
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
7BQ0
  • Download 7bq0
  • View 7bq0
Molmil generated image of 7bq0
X-RAY STRUCTURE OF HUMAN PPARALPHA LIGAND BINDING DOMAIN-FENOFIBRIC ACID-SRC1 COACTIVATOR PEPTIDE CO-CRYSTALS OBTAINED BY DELIPIDATION AND CO-CRYSTALLIZATION
Descriptor:Peroxisome proliferator-activated receptor alpha, 15-meric peptide from Nuclear receptor coactivator 1, 2-[4-(4-chlorobenzene-1-carbonyl)phenoxy]-2-methylpropanoic acid
Authors:Kamata, S., Ishikawa, R., Akahane, M., Oyama, T., Ishii, I.
Deposit date:2020-03-23
Release date:2020-11-11
Last modified:2020-12-02
Method:X-RAY DIFFRACTION (1.771 Å)
Cite:PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
171588
数据于2020-11-25公开中