3VWV

crystal structure of N-terminally truncated peroxiredoxin 4 from M. musculus

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Functional Information from GO Data

ChainGOidnamespacecontents
A0005623cellular_componentcell
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005783cellular_componentendoplasmic reticulum
A0005615cellular_componentextracellular space
A0005739cellular_componentmitochondrion
A0005790cellular_componentsmooth endoplasmic reticulum
A0042803molecular_functionprotein homodimerization activity
A0008379molecular_functionthioredoxin peroxidase activity
A0045454biological_processcell redox homeostasis
A0030198biological_processextracellular matrix organization
A0042744biological_processhydrogen peroxide catabolic process
A0008584biological_processmale gonad development
A2000255biological_processnegative regulation of male germ cell proliferation
A0055114biological_processoxidation-reduction process
A0018401biological_processpeptidyl-proline hydroxylation to 4-hydroxy-L-proline
A0022417biological_processprotein maturation by protein folding
A0072593biological_processreactive oxygen species metabolic process
A0006979biological_processresponse to oxidative stress
A0007283biological_processspermatogenesis
B0005623cellular_componentcell
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005783cellular_componentendoplasmic reticulum
B0005615cellular_componentextracellular space
B0005739cellular_componentmitochondrion
B0005790cellular_componentsmooth endoplasmic reticulum
B0042803molecular_functionprotein homodimerization activity
B0008379molecular_functionthioredoxin peroxidase activity
B0045454biological_processcell redox homeostasis
B0030198biological_processextracellular matrix organization
B0042744biological_processhydrogen peroxide catabolic process
B0008584biological_processmale gonad development
B2000255biological_processnegative regulation of male germ cell proliferation
B0055114biological_processoxidation-reduction process
B0018401biological_processpeptidyl-proline hydroxylation to 4-hydroxy-L-proline
B0022417biological_processprotein maturation by protein folding
B0072593biological_processreactive oxygen species metabolic process
B0006979biological_processresponse to oxidative stress
B0007283biological_processspermatogenesis
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC17BINDING SITE FOR RESIDUE 1PE A 301
ChainResidue
ALYS102
ALEU104
AASP108
AHOH549
BASP108
BHOH344
BHOH472

AC23BINDING SITE FOR RESIDUE ACY A 302
ChainResidue
ALEU121
AHIS200
AHOH551

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
1PE_3vwv_A_3017PENTAETHYLENE GLYCOL binding site
ChainResidueligand
AILE97-ASN981PE: PENTAETHYLENE GLYCOL
ALYS102-LEU1041PE: PENTAETHYLENE GLYCOL
AASP108-TYR1091PE: PENTAETHYLENE GLYCOL

ACY_3vwv_A_3024ACETIC ACID binding site
ChainResidueligand
APRO120-LEU121ACY: ACETIC ACID
ATHR124ACY: ACETIC ACID
AHIS200ACY: ACETIC ACID

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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI11Cysteine sulfenic acid (-SOH) intermediate (By similarity).
ChainResidueDetails
ACYS62

SWS_FT_FI21Cysteine sulfenic acid (-SOH) intermediate (By similarity).
ChainResidueDetails
BCYS62

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Catalytic Information from CSA

site_idNumber of ResiduesDetails