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6AZ3
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CRYO-EM STRUCTURE OF OF THE LARGE SUBUNIT OF LEISHMANIA RIBOSOME BOUND TO PAROMOMYCIN
Descriptor:ribosomal protein uL2, ribosomal protein uL3, ribosomal protein uL4, ...
Authors:Shalev-Benami, M., Zhang, Y., Rozenberg, H., Nobe, Y., Taoka, M., Matzov, D., Zimmerman, E., Bashan, A., Isobe, T., Jaffe, C.L., Yonath, A., Skiniotis, G.
Deposit date:2017-09-09
Release date:2017-12-06
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
4R07
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH ORN06
Descriptor:Toll-like receptor 8, URIDINE, 3'-O-[(R)-{[(2R,3aR,4R,6R,6aR)-6-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-hydroxy-2-oxidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]methoxy}(hydroxy)phosphoryl]uridine 5'-(dihydrogen phosphate), ...
Authors:Tanji, H., Ohto, U., Shibata, T., Taoka, M., Yamauchi, Y., Isobe, T., Miyake, K., Shimizu, T.
Deposit date:2014-07-30
Release date:2015-01-14
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Toll-like receptor 8 senses degradation products of single-stranded RNA
Nat.Struct.Mol.Biol., 22, 2015
6AZ1
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CRYO-EM STRUCTURE OF THE SMALL SUBUNIT OF LEISHMANIA RIBOSOME BOUND TO PAROMOMYCIN
Descriptor:Ribosomal protein s1e, ribosomal protein S2, ribosomal protein S3, ...
Authors:Shalev-Benami, M., Zhang, Y., Rozenberg, H., Matzov, D., Zimmerman, E., Bashan, A., Jaffe, C.L., Yonath, A., Skiniotis, G.
Deposit date:2017-09-09
Release date:2017-12-06
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
4R08
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH SSRNA40
Descriptor:Toll-like receptor 8, URIDINE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2014-07-30
Release date:2015-01-14
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Toll-like receptor 8 senses degradation products of single-stranded RNA.
Nat.Struct.Mol.Biol., 22, 2015
4R09
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH ORN06S
Descriptor:Toll-like receptor 8, URIDINE, O-[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-2-({[(S)-({(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-2-[(thiophosphonooxy)methyl]tetrahydrofuran-3-yl}oxy)(sulfanyl)phosphoryl]oxy}methyl)-4-hydroxytetrahydrofuran-3-yl] dihydrogen (S)-phosphorothioate, ...
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2014-07-30
Release date:2015-01-14
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Toll-like receptor 8 senses degradation products of single-stranded RNA.
Nat.Struct.Mol.Biol., 22, 2015
4R0A
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH URIDINE MONONUCLEOSIDE
Descriptor:Toll-like receptor 8, URIDINE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2014-07-30
Release date:2015-01-14
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toll-like receptor 8 senses degradation products of single-stranded RNA.
Nat.Struct.Mol.Biol., 22, 2015
5GMF
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CRYSTAL STRUCTURE OF MONKEY TLR7 IN COMPLEX WITH GUANOSINE AND POLYU
Descriptor:Toll-like receptor 7, RNA (5'-R(P*UP*UP*UP*U)-3'), CALCIUM ION, ...
Authors:Zhang, Z., Ohto, U., Shimizu, T.
Deposit date:2016-07-14
Release date:2016-11-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
Immunity, 45, 2016
5GMG
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CRYSTAL STRUCTURE OF MONKEY TLR7 IN COMPLEX WITH LOXORIBINE AND POLYU
Descriptor:Toll-like receptor 7, RNA (5'-R(P*UP*UP*UP*U)-3'), N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhang, Z., Ohto, U., Shimizu, T.
Deposit date:2016-07-14
Release date:2016-11-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
Immunity, 45, 2016
5GMH
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CRYSTAL STRUCTURE OF MONKEY TLR7 IN COMPLEX WITH R848
Descriptor:Toll-like receptor 7, 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhang, Z., Ohto, U., Shimizu, T.
Deposit date:2016-07-14
Release date:2016-11-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
Immunity, 45, 2016
2NSQ
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF THE HUMAN E3 UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE PROTEIN
Descriptor:E3 ubiquitin-protein ligase NEDD4-like protein, 1,2-ETHANEDIOL, GLYCEROL
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-11-06
Release date:2006-12-19
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
To be Published