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2JNR
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DISCOVERY AND OPTIMIZATION OF A NATURAL HIV-1 ENTRY INHIBITOR TARGETING THE GP41 FUSION PEPTIDE
Descriptor:VIR165, ENV polyprotein
Authors:Munch, J., Standker, L., Adermann, K., Schulz, A., Pohlmann, S., Chaipan, C., Biet, T., Peters, T., Meyer, B., Wilhelm, D., Lu, H., Jing, W., Jiang, S., Forssmann, W., Kirchhoff, F.
Deposit date:2007-02-01
Release date:2007-05-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide.
Cell(Cambridge,Mass.), 129, 2007
4BG7
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BACTERIOPHAGE T5 HOMOLOG OF THE EUKARYOTIC TRANSCRIPTION COACTIVATOR PC4 IMPLICATED IN RECOMBINATION-DEPENDENT DNA REPLICATION
Descriptor:PUTATIVE TRANSCRIPTIONAL COACTIVATOR P15
Authors:Steigemann, B., Schulz, A., Hinrichs, W., Werten, S.
Deposit date:2013-03-24
Release date:2013-09-11
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bacteriophage T5 Encodes a Homolog of the Eukaryotic Transcription Coactivator Pc4 Implicated in Recombination-Dependent DNA Replication.
J.Mol.Biol., 425, 2013
1H0Z
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LEKTI DOMAIN SIX
Descriptor:SERINE PROTEASE INHIBITOR KAZAL-TYPE 5, CONTAINS HEMOFILTRATE PEPTIDE HF6478, HEMOFILTRATE PEPTIDE HF7665
Authors:Lauber, T., Roesch, P., Marx, U.C.
Deposit date:2002-07-01
Release date:2003-06-26
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Homologous Proteins with Different Folds: The Three-Dimensional Structures of Domains 1 and 6 of the Multiple Kazal-Type Inhibitor Lekti
J.Mol.Biol., 328, 2003
1HDL
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LEKTI DOMAIN ONE
Descriptor:SERINE PROTEINASE INHIBITOR LEKTI
Authors:Lauber, T., Roesch, P., Marx, U.C.
Deposit date:2000-11-16
Release date:2001-11-15
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Homologous Proteins with Different Folds: The Three-Dimensional Structures of Domains 1 and 6 of the Multiple Kazal-Type Inhibitor Lekti
J.Mol.Biol., 328, 2003
5OR2
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CRYSTAL STRUCTURES OF PYR1/HAB1 IN COMPLEX WITH SYNTHETIC ANALOGUES OF ABSCISIC ACID
Descriptor:Abscisic acid receptor PYR1, Protein phosphatase 2C 16, (2~{Z},4~{E})-3-cyclopropyl-5-[(1~{S})-2,6,6-trimethyl-1-oxidanyl-4-oxidanylidene-cyclohex-2-en-1-yl]penta-2,4-dienoic acid, ...
Authors:Freigang, J.
Deposit date:2017-08-15
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the in Vitro and in Vivo SAR of Abscisic Acid - Exploring Unprecedented Variations of the Side Chain via Cross-Coupling-Mediated Syntheses
Eur.J.Org.Chem., 2018
5OR6
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CRYSTAL STRUCTURES OF PYR1/HAB1 IN COMPLEX WITH SYNTHETIC ANALOGUES OF ABSCISIC ACID
Descriptor:Abscisic acid receptor PYR1, Protein phosphatase 2C 16, (~{E})-3-(trifluoromethyl)-5-[(1~{S})-2,6,6-trimethyl-1-oxidanyl-4-oxidanylidene-cyclohex-2-en-1-yl]pent-2-en-4-ynoic acid, ...
Authors:Freigang, J.
Deposit date:2017-08-15
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights into the in Vitro and in Vivo SAR of Abscisic Acid - Exploring Unprecedented Variations of the Side Chain via Cross-Coupling-Mediated Syntheses
Eur.J.Org.Chem., 2018
2L6S
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EFFICACY OF AN HIV-1 ENTRY INHIBITOR TARGETING THE GP41 FUSION PEPTIDE
Descriptor:VIR-576
Authors:Forssmann, W., The, Y., Stoll, M., Adermann, K., Albrecht, U., Barlos, K., Busmann, A., Canales-Mayordomo, A., Gimenez-Gallego, G., Hirsch, J., Jimenez-Barbero, J., Meyer-Olson, D., Muench, J., Perez-Castells, J., Standker, L., Kirchhoff, F., Schmidt, R.E.
Deposit date:2010-11-24
Release date:2011-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Sci Transl Med, 2, 2010
2L6T
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EFFICACY OF AN HIV-1 ENTRY INHIBITOR TARGETING THE GP41 FUSION PEPTIDE
Descriptor:VIR-576
Authors:Forssmann, W., The, Y., Stoll, M., Adermann, K., Albrecht, U., Barlos, K., Busmann, A., Can les-Mayordomo, A., Gimenez-Gallego, G., Hirsch, J., Jimenez-Barbero, J., Meyer-Olson, D., Muench, J., Perez-Castells, J., Staendker, L., Kirchhoff, F., Schmidt, R.E.
Deposit date:2010-11-24
Release date:2011-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Sci Transl Med, 2, 2010