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6NIY
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A HIGH-RESOLUTION CRYO-ELECTRON MICROSCOPY STRUCTURE OF A CALCITONIN RECEPTOR-HETEROTRIMERIC GS PROTEIN COMPLEX
Descriptor:Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Nanobody35, Calcitonin receptor, ...
Authors:dal Maso, E., Glukhova, A., Zhu, Y., Garcia-Nafria, J., Tate, C.G., Atanasio, S., Reynolds, C.A., Ramirez-Aportela, E., Carazo, J.-M., Hick, C.A., Furness, S.G.B., Hay, D.L., Liang, Y.-L., Miller, L.J., Christopoulos, A., Wang, M.-W., Wootten, D., Sexton, P.M.
Deposit date:2019-01-02
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:The Molecular Control of Calcitonin Receptor Signaling
Acs Pharmacol Transl Sci, 2019
6E3Y
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CRYO-EM STRUCTURE OF THE ACTIVE, GS-PROTEIN COMPLEXED, HUMAN CGRP RECEPTOR
Descriptor:Calcitonin gene-related peptide 1, Nanobody 35, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Liang, Y.L., Khoshouei, M., Deganutti, G., Glukhova, A., Koole, C., Peat, T.S., Radjainia, M., Plitzko, J.M., Baumeister, W., Miller, L.J., Hay, D.L., Christopoulos, A., Reynolds, C.A., Wootten, D., Sexton, P.M.
Deposit date:2018-07-16
Release date:2018-09-19
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor.
Nature, 561, 2018
6ORV
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NON-PEPTIDE AGONIST (TT-OAD2) BOUND TO THE GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR
Descriptor:Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Belousoff, M.J., Liang, Y.L., Danev, R.
Deposit date:2019-05-01
Release date:2020-01-08
Last modified:2020-01-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Activation of the GLP-1 receptor by a non-peptidic agonist.
Nature, 577, 2020