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4ACI
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STRUCTURE OF THE C. GLUTAMICUM ACNR CRYSTAL FORM II
Descriptor:HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR, MAGNESIUM ION, GLYCEROL, ...
Authors:Garcia-Nafria, J., Baumgart, M., Turkenburg, J.P., Wilkinson, A.J., Bott, M., Wilson, K.S.
Deposit date:2011-12-15
Release date:2012-12-26
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket.
J.Biol.Chem., 288, 2013
4AF5
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STRUCTURE OF THE C. GLUTAMICUM ACNR CRYSTAL FORM I
Descriptor:HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR COMPND 2, MAGNESIUM ION, CITRIC ACID
Authors:Garcia-Nafria, J., Baumgart, M., Turkenburg, J.P., Wilkinson, A.J., Bott, M., Wilson, K.S.
Deposit date:2012-01-17
Release date:2013-01-23
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket.
J.Biol.Chem., 288, 2013
4AOO
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B. SUBTILIS DUTPASE YNCF IN COMPLEX WITH DU PPI AND MG IN H32
Descriptor:PROBABLE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YNCF, 2'-DEOXYURIDINE, PYROPHOSPHATE 2-, ...
Authors:Garcia-Nafria, J., Timm, J., Harrison, C., Turkenburg, J.P., Wilson, K.S.
Deposit date:2012-03-29
Release date:2013-04-17
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
4APZ
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STRUCTURE OF B. SUBTILIS GENOMIC DUTPASE YNCF IN COMPLEX WITH DU, PPI AND MG IN P1
Descriptor:PROBABLE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YNCF, 2'-DEOXYURIDINE, PYROPHOSPHATE 2-, ...
Authors:Garcia-Nafria, J., Timm, J., Harrison, C., Turkenburg, J.P., Wilson, K.S.
Deposit date:2012-04-11
Release date:2013-04-24
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
2XCE
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STRUCTURE OF YNCF IN COMPLEX WITH DUPNHPP
Descriptor:PROBABLE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YNCF, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Garcia-Nafria, J., Burchell, L., Takezawa, M., Rzechorzek, N., Fogg, M., Wilson, K.S.
Deposit date:2010-04-22
Release date:2010-08-11
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Structure of the Genomic Bacillus Subtilis Dutpase: Novel Features in the Phe-Lid.
Acta Crystallogr.,Sect.D, 66, 2010
2XX6
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STRUCTURE OF THE BACILLUS SUBTILIS PROPHAGE DUTPASE, YOSS
Descriptor:SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS
Authors:Garcia-Nafria, J., Harkiolaki, M., Persson, R., Fogg, M.J., Wilson, K.S.
Deposit date:2010-11-08
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Structure of Bacillus Subtilis Sp Beta Prophage Dutpase and its Complexes with Two Nucleotides
Acta Crystallogr.,Sect.D, 67, 2011
2XY3
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STRUCTURE OF THE BACILLUS SUBTILIS PROPHAGE DUTPASE WITH DUPNHPP
Descriptor:SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION
Authors:Garcia-Nafria, J., Harkiolaki, M., Persson, R., Fogg, M.J., Wilson, K.S.
Deposit date:2010-11-12
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The Structure of Bacillus Subtilis Sp Beta Prophage Dutpase and its Complexes with Two Nucleotides
Acta Crystallogr.,Sect.D, 67, 2011
2Y1T
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BACILLUS SUBTILIS PROPHAGE DUTPASE IN COMPLEX WITH DUDP
Descriptor:SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS, DEOXYURIDINE-5'-DIPHOSPHATE
Authors:Garcia-Nafria, J., Harkiolaki, M., Persson, R., Fogg, M.J., Wilson, K.S.
Deposit date:2010-12-10
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The Structure of Bacillus Subtilis Sp Beta Prophage Dutpase and its Complexes with Two Nucleotides
Acta Crystallogr.,Sect.D, 67, 2011
4AC6
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CORYNEBACTERIUM GLUTAMICUM ACNR AU DERIVATIVE STRUCTURE
Descriptor:HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR, GOLD ION
Authors:Garcia-Nafria, J., Baumgart, M., Turkenburg, J.P., Wilkinson, A.J., Bott, M., Wilson, K.S.
Deposit date:2011-12-14
Release date:2012-12-26
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket.
J.Biol.Chem., 288, 2013
4AO5
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B. SUBTILIS PROPHAGE DUTPASE YOSS IN COMPLEX WITH DUMP
Descriptor:SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEO TIDOHYDROLASE YOSS, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, SODIUM ION
Authors:Garcia-Nafria, J., Harrison, C., Turkenburg, J.P., Wilson, K.S.
Deposit date:2012-03-23
Release date:2013-04-03
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
6G79
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COUPLING SPECIFICITY OF HETEROTRIMERIC GO TO THE SEROTONIN 5-HT1B RECEPTOR
Descriptor:Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(o) subunit alpha, ...
Authors:Garcia-Nafria, J., Nehme, R., Edwards, P., Tate, C.G.
Deposit date:2018-04-05
Release date:2018-06-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Cryo-EM structure of the serotonin 5-HT1Breceptor coupled to heterotrimeric Go.
Nature, 558, 2018
6GDG
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CRYO-EM STRUCTURE OF THE ADENOSINE A2A RECEPTOR BOUND TO A MINIGS HETEROTRIMER
Descriptor:TrxA,Adenosine receptor A2a, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Garcia-Nafria, J., Lee, Y.
Deposit date:2018-04-23
Release date:2018-05-16
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Cryo-EM structure of the adenosine A2Areceptor coupled to an engineered heterotrimeric G protein.
Elife, 7, 2018
4AOZ
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B. SUBTILIS DUTPASE YNCF IN COMPLEX WITH DU, PPI AND MG (P212121)
Descriptor:PROBABLE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YNCF, 2'-DEOXYURIDINE, PYROPHOSPHATE 2-, ...
Authors:Timm, J., Garcia-Nafria, J., Harrison, C., Turkenburg, J.P., Wilson, K.S.
Deposit date:2012-03-30
Release date:2013-05-01
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
4B0H
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B. SUBTILIS DUTPASE YNCF IN COMPLEX WITH DU, PPI AND MG B (P212121)
Descriptor:PROBABLE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YNCF, 2'-DEOXYURIDINE, CHLORIDE ION, ...
Authors:Timm, J., Garcia-Nafria, J., Harrison, C., Turkenburg, J.P., Wilson, K.S.
Deposit date:2012-07-02
Release date:2013-05-15
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
5FWX
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CRYSTAL STRUCTURE OF THE AMPA RECEPTOR GLUA2/A4 N-TERMINAL DOMAIN HETERODIMER
Descriptor:GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR 4, SULFATE ION, ...
Authors:Garcia-Nafria, J., Herguedas, B., Greger, I.H.
Deposit date:2016-02-21
Release date:2016-03-16
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Organization of Heteromeric Ampa-Type Glutamate Receptors.
Science, 352, 2016
6FLR
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SUPER-OPEN STRUCTURE OF THE AMPAR GLUA3 N-TERMINAL DOMAIN
Descriptor:Glutamate receptor 3, N-ACETYL-D-GLUCOSAMINE
Authors:Garcia-Nafria, J.
Deposit date:2018-01-27
Release date:2018-12-19
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain.
Structure, 27, 2019
5FWY
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CRYSTAL STRUCTURE OF THE AMPA RECEPTOR GLUA2/A3 N-TERMINAL DOMAIN HETERODIMER
Descriptor:GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR 3, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Herguedas, B., Garcia-Nafria, J., Greger, I.H.
Deposit date:2016-02-21
Release date:2016-03-16
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structure and Organization of Heteromeric Ampa-Type Glutamate Receptors.
Science, 352, 2016
5IDE
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CRYO-EM STRUCTURE OF GLUA2/3 AMPA RECEPTOR HETEROTETRAMER (MODEL I)
Descriptor:Glutamate receptor 2, Glutamate receptor 3
Authors:Herguedas, B., Garcia-Nafria, J., Fernandez-Leiro, R., Greger, I.H.
Deposit date:2016-02-24
Release date:2016-03-16
Last modified:2017-10-11
Method:ELECTRON MICROSCOPY (8.25 Å)
Cite:Structure and organization of heteromeric AMPA-type glutamate receptors.
Science, 352, 2016
5IDF
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CRYO-EM STRUCTURE OF GLUA2/3 AMPA RECEPTOR HETEROTETRAMER (MODEL II)
Descriptor:Glutamate receptor 2, Glutamate receptor 3
Authors:Herguedas, B., Garcia-Nafria, J., Fernandez-Leiro, R., Greger, I.H.
Deposit date:2016-02-24
Release date:2016-03-16
Last modified:2017-10-11
Method:ELECTRON MICROSCOPY (10.31 Å)
Cite:Structure and organization of heteromeric AMPA-type glutamate receptors.
Science, 352, 2016
6FPJ
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STRUCTURE OF THE AMPAR GLUA3 N-TERMINAL DOMAIN BOUND TO PHOSPHATE
Descriptor:Glutamate receptor 3, N-ACETYL-D-GLUCOSAMINE, PHOSPHATE ION, ...
Authors:Herguedas, B., Garcia-Nafria, J., Greger, I.
Deposit date:2018-02-09
Release date:2018-12-19
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain.
Structure, 27, 2019
6GBU
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CRYSTAL STRUCTURE OF THE SECOND SH3 DOMAIN OF FCHSD2 (SH3-2) IN COMPLEX WITH THE FOURTH SH3 DOMAIN OF ITSN1 (SH3D)
Descriptor:F-BAR and double SH3 domains protein 2, Intersectin-1
Authors:Almeida-Souza, L., Frank, R., Garcia-Nafria, J., Colussi, A., Gunawardana, N., Johnson, C.M., Yu, M., Howard, G., Andrews, B., Vallis, Y., McMahon, H.T.
Deposit date:2018-04-16
Release date:2018-06-13
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (3.44 Å)
Cite:A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits.
Cell, 174, 2018
6NIY
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A HIGH-RESOLUTION CRYO-ELECTRON MICROSCOPY STRUCTURE OF A CALCITONIN RECEPTOR-HETEROTRIMERIC GS PROTEIN COMPLEX
Descriptor:Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Nanobody35, Calcitonin receptor, ...
Authors:dal Maso, E., Glukhova, A., Zhu, Y., Garcia-Nafria, J., Tate, C.G., Atanasio, S., Reynolds, C.A., Ramirez-Aportela, E., Carazo, J.-M., Hick, C.A., Furness, S.G.B., Hay, D.L., Liang, Y.-L., Miller, L.J., Christopoulos, A., Wang, M.-W., Wootten, D., Sexton, P.M.
Deposit date:2019-01-02
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:The Molecular Control of Calcitonin Receptor Signaling
Acs Pharmacol Transl Sci, 2019
6QKC
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GLUA1/2 IN COMPLEX WITH AUXILIARY SUBUNIT GAMMA-8
Descriptor:Glutamate receptor 1, Glutamate receptor 2, Voltage-dependent calcium channel gamma-8 subunit, ...
Authors:Herguedas, B., Garcia-Nafria, J., Greger, I.G.
Deposit date:2019-01-28
Release date:2019-03-27
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8.
Science, 364, 2019
6QKZ
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FULL LENGTH GLUA1/2-GAMMA8 COMPLEX
Descriptor:GluA1, Glutamate receptor 2, Voltage-dependent calcium channel gamma-8 subunit, ...
Authors:Herguedas, B., Garcia-Nafria, J., Greger, I.G.
Deposit date:2019-01-30
Release date:2019-03-27
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8.
Science, 364, 2019
2X36
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STRUCTURE OF THE PROTEOLYTIC DOMAIN OF THE HUMAN MITOCHONDRIAL LON PROTEASE
Descriptor:LON PROTEASE HOMOLOG, MITOCHONDRIAL
Authors:Garcia, J., Ondrovicova, G., Blagova, E., Levdikov, V.M., Bauer, J.A., Kutejova, E., Wilkinson, A.J., Wilson, K.S.
Deposit date:2010-01-21
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Catalytic Domain of the Human Mitochondrial Lon Protease: Proposed Relation of Oligomer Formation and Activity.
Protein Sci., 19, 2010
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