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3ZEF
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CRYSTAL STRUCTURE OF PRP8:AAR2 COMPLEX: SECOND CRYSTAL FORM AT 3.1 ANGSTROM RESOLUTION
Descriptor:A1 CISTRON-SPLICING FACTOR AAR2, PRE-MRNA-SPLICING FACTOR 8
Authors:Galej, W.P., Oubridge, C., Newman, A.J., Nagai, K.
Deposit date:2012-12-05
Release date:2013-01-30
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of Prp8 Reveals Active Site Cavity of the Spliceosome
Nature, 493, 2013
4I43
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CRYSTAL STRUCTURE OF PRP8:AAR2 COMPLEX
Descriptor:A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
Authors:Galej, W.P., Oubridge, C., Newman, A.J., Nagai, K.
Deposit date:2012-11-27
Release date:2013-01-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Prp8 reveals active site cavity of the spliceosome.
Nature, 493, 2013
5LJ3
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STRUCTURE OF THE CORE OF THE YEAST SPLICEOSOME IMMEDIATELY AFTER BRANCHING
Descriptor:U5 snRNA (small nuclear RNA), Exon 1 (5' exon) of UBC4 pre-mRNA, Intron of UBC4 pre-mRNA, ...
Authors:Galej, W.P., Wilkinson, M.F., Fica, S.M., Oubridge, C., Newman, A.J., Nagai, K.
Deposit date:2016-07-17
Release date:2016-08-03
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
5LJ5
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OVERALL STRUCTURE OF THE YEAST SPLICEOSOME IMMEDIATELY AFTER BRANCHING.
Descriptor:U5 snRNA (small nuclear RNA), Exon 1 (5' exon) of UBC4 pre-mRNA, Intron of UBC4 pre-mRNA, ...
Authors:Galej, W.P., Wilkinson, M.F., Fica, S.M., Oubridge, C., Newman, A.J., Nagai, K.
Deposit date:2016-07-17
Release date:2016-08-31
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
5MPS
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STRUCTURE OF A SPLICEOSOME REMODELED FOR EXON LIGATION
Descriptor:Yeast UBC4 gene for ubiquitin-conjugating enzyme, UBC4 gene exon, U2 snRNA, ...
Authors:Fica, S.M., Oubridge, C., Galej, W.P., Wilkinson, M.E., Newman, A.J., Bai, X.-C., Nagai, K.
Deposit date:2016-12-18
Release date:2017-01-18
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MQ0
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STRUCTURE OF A SPLICEOSOME REMODELED FOR EXON LIGATION
Descriptor:Yeast UBC4 gene for ubiquitin-conjugating enzyme, 5'-EXON OF UBC4 PRE-MRNA, S.cerevisiae chromosome II reading frame ORF YBR230c, ...
Authors:Fica, S.M., Oubridge, C., Galej, W.P., Wilkinson, M.E., Newman, A.J., Bai, X.-C., Nagai, K.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5GAM
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FOOT REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP
Descriptor:U5 snRNA, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-02-03
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
5GAN
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THE OVERALL STRUCTURE OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP AT 3.7 ANGSTROM
Descriptor:U4 snRNA, U6 snRNA, Pre-mRNA-splicing factor 8, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5GAO
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HEAD REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP
Descriptor:Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5GAP
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BODY REGION OF THE U4/U6.U5 TRI-SNRNP
Descriptor:U4 snRNA, 5' region, nucleotides 1-67, ...
Authors:Nguyen, T.H.D., Galej, W.P., Oubridge, C., Bai, X.C., Newman, A., Scheres, S., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
6EXN
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POST-CATALYTIC P COMPLEX SPLICEOSOME WITH 3' SPLICE SITE DOCKED
Descriptor:U2 snRNA, U5 snRNA, U6 snRNA, ...
Authors:Wilkinson, M.E., Fica, S.M., Galej, W.P., Norman, C.M., Newman, A.J., Nagai, K.
Deposit date:2017-11-08
Release date:2018-01-17
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
6S5T
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LEGIONELLA PNEUMOPHILA SIDJ-HUMAN CALMODULIN COMPLEX
Descriptor:SidJ, Calmodulin-2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Bhogaraju, S., Galej, W.P., Pfleiderer, M.M., Adams, M.
Deposit date:2019-07-02
Release date:2019-07-24
Last modified:2019-08-28
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin catalysed glutamylation.
Nature, 572, 2019
4BGD
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CRYSTAL STRUCTURE OF BRR2 IN COMPLEX WITH THE JAB1/MPN DOMAIN OF PRP8
Descriptor:PRE-MRNA-SPLICING HELICASE BRR2, PRE-MRNA-SPLICING FACTOR 8, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Nguyen, T.H.D., Li, J., Nagai, K.
Deposit date:2013-03-25
Release date:2013-05-29
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Brr2-Prp8 Interactions and Implications for U5 Snrnp Biogenesis and the Spliceosome Active Site
Structure, 21, 2013