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5O31
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MITOCHONDRIAL COMPLEX I IN THE DEACTIVE STATE
Descriptor:NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, ...
Authors:Blaza, J.N., Vinothkumar, K.R., Hirst, J.
Deposit date:2017-05-23
Release date:2018-01-17
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Structure of the Deactive State of Mammalian Respiratory Complex I.
Structure, 26, 2018
5NG5
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MULTI-DRUG EFFLUX; MEMBRANE TRANSPORT; RND SUPERFAMILY; DRUG RESISTANCE
Descriptor:Multidrug efflux pump subunit AcrA, Outer membrane protein TolC, Multidrug efflux pump subunit AcrB, ...
Authors:Wang, Z., Fan, G., Hryc, C.F., Blaza, J.N., Serysheva, I.I., Schmid, M.F., Chiu, W., Luisi, B.F., Du, D.
Deposit date:2017-03-16
Release date:2017-04-19
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
5NIK
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STRUCTURE OF THE MACAB-TOLC ABC-TYPE TRIPARTITE MULTIDRUG EFFLUX PUMP
Descriptor:Outer membrane protein TolC, Macrolide export protein MacA, Macrolide export ATP-binding/permease protein MacB
Authors:Fitzpatrick, A.W.P., Llabres, S., Neuberger, A., Blaza, J.N., Bai, X.-C., Okada, U., Murakami, S., van Veen, H.W., Zachariae, U., Scheres, S.H.W., Luisi, B.F., Du, D.
Deposit date:2017-03-24
Release date:2017-05-24
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
5NIL
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STRUCTURE OF THE MACAB-TOLC ABC-TYPE TRIPARTITE MULTIDRUG EFFLUX PUMP-MACB SECTION
Descriptor:Outer membrane protein TolC, Macrolide export protein MacA, Macrolide export ATP-binding/permease protein MacB
Authors:Fitzpatrick, A.W.P., Llabres, S., Neuberger, A., Blaza, J.N., Bai, X.-C., Okada, U., Murakami, S., van Veen, H.W., Zachariae, U., Scheres, S.H.W., Luisi, B.F., Du, D.
Deposit date:2017-03-24
Release date:2017-05-24
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
5V5S
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MULTI-DRUG EFFLUX; MEMBRANE TRANSPORT; RND SUPERFAMILY; DRUG RESISTANCE
Descriptor:Outer membrane protein TolC, Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB
Authors:wang, Z., fan, G., Hryc, C.F., Blaza, J.N., Serysheva, I.I., Schmid, M.F., Chiu, W., Luisi, B.F., Du, D.
Deposit date:2017-03-15
Release date:2017-04-19
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
6G2J
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MOUSE MITOCHONDRIAL COMPLEX I IN THE ACTIVE STATE
Descriptor:NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, ...
Authors:Agip, A.N.A., Blaza, J.N., Bridges, H.R., Viscomi, C., Rawson, S., Muench, S.P., Hirst, J.
Deposit date:2018-03-23
Release date:2018-06-06
Last modified:2018-08-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states.
Nat. Struct. Mol. Biol., 25, 2018
6G72
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MOUSE MITOCHONDRIAL COMPLEX I IN THE DEACTIVE STATE
Descriptor:NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, ...
Authors:Agip, A.N.A., Blaza, J.N., Bridges, H.R., Viscomi, C., Rawson, S., Muench, S.P., Hirst, J.
Deposit date:2018-04-04
Release date:2018-06-06
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states.
Nat. Struct. Mol. Biol., 25, 2018
6ZR2
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CRYO-EM STRUCTURE OF RESPIRATORY COMPLEX I IN THE ACTIVE STATE FROM MUS MUSCULUS AT 3.1 A
Descriptor:NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, ...
Authors:Bridges, H.R., Blaza, J.N., Agip, A.N.A., Hirst, J.
Deposit date:2020-07-10
Release date:2020-10-21
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
6ZTQ
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CRYO-EM STRUCTURE OF RESPIRATORY COMPLEX I FROM MUS MUSCULUS INHIBITED BY PIERICIDIN A AT 3.0 A
Descriptor:NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, ...
Authors:Bridges, H.R., Blaza, J.N., Agip, A.N.A., Hirst, J.
Deposit date:2020-07-20
Release date:2020-10-21
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
5KMP
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THE STRUCTURE OF G164E VARIANT OF TYPE II NADH DEHYDROGENASE FROM CALDALKALIBACILLUS THERMARUM
Descriptor:FAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Cook, G.M., Aragao, D., Nakatani, Y.
Deposit date:2016-06-27
Release date:2017-01-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The mechanism of catalysis by type-II NADH:quinone oxidoreductases.
Sci Rep, 7, 2017
5KMQ
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THE STRUCTURE OF I379E VARIANT OF TYPE II NADH DEHYDROGENASE FROM CALDALKALIBACILLUS THERMARUM
Descriptor:FAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Cook, G.M., Aragao, D., Nakatani, Y.
Deposit date:2016-06-27
Release date:2017-01-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The mechanism of catalysis by type-II NADH:quinone oxidoreductases.
Sci Rep, 7, 2017
5KMR
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THE STRUCTURE OF TYPE II NADH DEHYDROGENASE FROM CALDALKALIBACILLUS THERMARUM COMPLEXED WITH NAD+ AT 3.0 ANGSTROM RESOLUTION.
Descriptor:FAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Cook, G.M., Aragao, D., Nakatani, Y.
Deposit date:2016-06-27
Release date:2017-01-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:The mechanism of catalysis by type-II NADH:quinone oxidoreductases.
Sci Rep, 7, 2017
5KMS
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THE STRUCTURE OF TYPE II NADH DEHYDROGENASE FROM CALDALKALIBACILLUS THERMARUM COMPLEXED WITH NAD+ AT 2.5 ANGSTROM RESOLUTION.
Descriptor:FAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Cook, G.M., Aragao, D., Nakatani, Y.
Deposit date:2016-06-27
Release date:2017-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The mechanism of catalysis by type-II NADH:quinone oxidoreductases.
Sci Rep, 7, 2017
5NC5
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CRYSTAL STRUCTURE OF ACRBZ IN COMPLEX WITH ANTIBIOTIC PUROMYCIN
Descriptor:Multidrug efflux pump subunit AcrB, DARPin, Multidrug efflux pump accessory protein AcrZ, ...
Authors:Du, D., Luisi, B.
Deposit date:2017-03-03
Release date:2017-04-12
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
5O66
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ASYMMETRIC ACRABZ-TOLC
Descriptor:Outer membrane protein TolC, Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, ...
Authors:Du, D., Luisi, B.F.
Deposit date:2017-06-05
Release date:2017-06-14
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump.
Elife, 6, 2017
171588
PDB entries from 2020-11-25