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2AAR
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STRUCTURE OF TRIGGER FACTOR BINDING DOMAIN IN BIOLOGICALLY HOMOLOGOUS COMPLEX WITH EUBACTERIAL RIBOSOME.
Descriptor:23S ribosomal RNA, 50S ribosomal protein L23, 50S ribosomal protein L29, ...
Authors:Baram, D., Pyetan, E., Sittner, A., Auerbach-Nevo, T., Bashan, A., Yonath, A.
Deposit date:2005-07-14
Release date:2005-08-23
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action
Proc.Natl.Acad.Sci.Usa, 102, 2005
2O43
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STRUCTURE OF 23S RRNA OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH THE MACROLIDE ERYTHROMYCYLAMINE
Descriptor:23S rRNA, (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-AMINO-6-{[(2S,3R,4S,6R)-4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-14-ETHYL-7,12,13-TRIHYDROXY-4-{[(2R,4R,5S,6S)-5-HYDROXY-4-METHOXY-4,6-DIMETHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-3,5,7,9,11,13-HEXAMETHYLOXACYCLOTETRADECAN-2-ONE
Authors:Pyetan, E., Baram, D., Auerbach-Nevo, T., Yonath, A.
Deposit date:2006-12-03
Release date:2007-12-04
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Chemical parameters influencing fine tuning in the binding of Macrolide antibiotics to the ribosomal tunnel
TO BE PUBLISHED
2O44
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STRUCTURE OF 23S RRNA OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH THE MACROLIDE JOSAMYCIN
Descriptor:23S rRNA, (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10S,12E,14Z,16R)-4-(ACETYLOXY)-10-HYDROXY-5-METHOXY-9,16-DIMETHYL-2-OXO-7-(2-OXOETHYL)OXACYCLOHEXADECA-12,14-DIEN-6-YL]OXY}-4-(DIMETHYLAMINO)-5-HYDROXY-2-METHYLTETRAHYDRO-2H-PYRAN-3-YL]OXY}-4-HYDROXY-2,4-DIMETHYLTETRAHYDRO-2H-PYRAN-3-YL 3-METHYLBUTANOATE
Authors:Pyetan, E., Daram, D., Auerbach-Nevo, T., Yonath, A.
Deposit date:2006-12-03
Release date:2007-12-04
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Chemical parameters influencing fine tuning in the binding of Macrolide antibiotics to the ribosomal tunnel
TO BE PUBLISHED
2O45
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STRUCTURE OF THE 23S RRNA OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH THE MACROLIDE RU-69874
Descriptor:23S rRNA, (3AS,4R,7R,8S,9S,10R,11R,13R,15R,15AR)-4-ETHYL-11-METHOXY-3A,7,9,11,13,15-HEXAMETHYL-2,6,14-TRIOXO-1-[4-(4-PYRIDIN-3-YL-1H-IMIDAZOL-1-YL)BUTYL]-10-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}TETRADECAHYDRO-2H-OXACYCLOTETRADECINO[4,3-D][1,3]OXAZOL-8-YL 2,6-DIDEOXY-3-C-METHYL-3-O-METHYL-ALPHA-L-RIBO-HEXOPYRANOSIDE
Authors:Baram, D., Pyetan, E., Auerbach-Nevo, T., Yonath, A.
Deposit date:2006-12-03
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Chemical Parameters Influencing Fine Tuning in the Binding of Macrolide Antibiotics to the Ribosomal Tunnel
TO BE PUBLISHED
2OGM
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH THE PLEUROMUTILIN DERIVATIVE SB-571519
Descriptor:23S ribosomal RNA, 50S ribosomal protein L3, (2S,3AR,4R,5S,6S,8R,9R,9AR,10R)-2,5-DIHYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROP[1]ENOCYCLOPENTA[8]ANNULEN-8-YL [(6-AMINOPYRIDAZIN-3-YL)CARBONYL]CARBAMATE
Authors:Davidovich, C., Bashan, A., Auerbach-Nevo, T., Yonath, A.
Deposit date:2007-01-07
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGN
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH THE PLEUROMUTILIN DERIVATIVE SB-280080
Descriptor:23S ribosomal RNA, 50S ribosomal protein L3, (3AS,4R,5S,6S,8R,9R,9AR,10R)-5-HYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROPANOCYCLOPENTA[8]ANNULEN-8-YL (PIPERIDIN-4-YLTHIO)ACETATE
Authors:Davidovich, C., Bashan, A., Auerbach-Nevo, T., Yonath, A.
Deposit date:2007-01-07
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGO
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH THE PLEUROMUTILIN DERIVATIVE RETAPAMULIN (SB-275833)
Descriptor:23S ribosomal RNA, 50S ribosomal protein L3, (3AS,4R,5S,6S,8R,9R,9AR,10R)-5-HYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROPANOCYCLOPENTA[8]ANNULEN-8-YL {[(3-EXO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL]THIO}ACETATE
Authors:Davidovich, C., Bashan, A., Auerbach-Nevo, T., Yonath, A.
Deposit date:2007-01-07
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3BKN
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THE STRUCTURE OF MYCOBACTERIAL BACTERIOFERRITIN
Descriptor:Bacterioferritin, ZINC ION, MAGNESIUM ION, ...
Authors:Janowski, R., Auerbach-Nevo, T., Weiss, M.S.
Deposit date:2007-12-07
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Bacterioferritin from Mycobacterium smegmatis contains zinc in its di-nuclear site.
Protein Sci., 17, 2008
3JQ4
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THE STRUCTURE OF THE COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM D. RADIODURANS WITH THE ANTIBIOTIC LANKACIDIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxopropanamide
Authors:Auerbach-Nevo, T., Mermershtain, I., Davidovich, C., Bashan, A., Rozenberg, H., Yonath, A.
Deposit date:2009-09-06
Release date:2010-09-08
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics
Proc.Natl.Acad.Sci.USA, 107, 2010