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5JI8
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CRYSTAL STRUCTURE OF THE BRD9 BROMODOMAIN AND HIT 1
Descriptor:Bromodomain-containing protein 9, 2-amino-1,3-benzothiazole-6-carboxamide
Authors:Wang, N., Li, F., Bao, H., Li, J., Wu, J., Ruan, K.
Deposit date:2016-04-22
Release date:2016-06-22
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains
Chembiochem, 17, 2016
5YJ8
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IDENTIFICATION OF A SMALL MOLECULE INHIBITOR FOR THE TUDOR DOMAIN OF TDRD3
Descriptor:Tudor domain-containing protein 3, 5-(aminomethyl)-1,3-dimethyl-benzimidazol-2-one, SULFATE ION
Authors:Liu, J., Ruan, K.
Deposit date:2017-10-09
Release date:2018-05-02
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Structural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit.
FEBS J., 285, 2018
4K6N
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CRYSTAL STRUCTURE OF YEAST 4-AMINO-4-DEOXYCHORISMATE LYASE
Descriptor:Aminodeoxychorismate lyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Dai, Y.-N., Chi, C.-B., Zhou, K., Cheng, W., Jiang, Y.-L., Ren, Y.-M., Chen, Y., Zhou, C.-Z.
Deposit date:2013-04-16
Release date:2013-07-10
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and catalytic mechanism of yeast 4-amino-4-deoxychorismate lyase
J.Biol.Chem., 288, 2013
2LUY
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SOLUTION STRUCTURE OF THE TANDEM ZINC FINGER DOMAIN OF FISSION YEAST STC1
Descriptor:Meiotic chromosome segregation protein P8B7.28c, ZINC ION
Authors:He, C., Shi, Y., Bayne, E., Wu, J.
Deposit date:2012-06-22
Release date:2013-05-08
Last modified:2013-06-12
Method:SOLUTION NMR
Cite:Structural analysis of Stc1 provides insights into the coupling of RNAi and chromatin modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
5GH9
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CRYSTAL STRUCTURE OF CBP BROMODOMAIN WITH H3K56AC PEPTIDE
Descriptor:CREB-binding protein, Histone H3
Authors:Xu, L.
Deposit date:2016-06-19
Release date:2017-06-21
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural insight into CBP bromodomain-mediated recognition of acetylated histone H3K56ac
FEBS J., 2017
5H1D
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CRYSTAL STRUCTURE OF C-TERMINAL OF RHOGDI2
Descriptor:Rho GDP-dissociation inhibitor 2
Authors:Liu, J.
Deposit date:2016-10-08
Release date:2016-10-26
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (1.494 Å)
Cite:NMR characterization of weak interactions between RhoGDI2 and fragment screening hits.
Biochim. Biophys. Acta, 1861, 2017
5H1T
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COMPLEX STRUCTURE OF TRIM24 PHD-BROMODOMAIN AND INHIBITOR 1
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, methyl 6-azanyl-3,4-dihydro-2H-quinoline-1-carboxylate, ...
Authors:Liu, J.
Deposit date:2016-10-11
Release date:2017-02-22
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network
FEBS J., 284, 2017
5H1U
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COMPLEX STRUCTURE OF TRIM24 PHD-BROMODOMAIN AND INHIBITOR 2
Descriptor:Transcription intermediary factor 1-alpha, 2-amino-1,3-benzothiazole-6-carboxamide, ZINC ION, ...
Authors:Liu, J.
Deposit date:2016-10-11
Release date:2017-02-22
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network
FEBS J., 284, 2017
5H1V
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COMPLEX STRUCTURE OF TRIM24 PHD-BROMODOMAIN AND INHIBITOR 6
Descriptor:Transcription intermediary factor 1-alpha, ZINC ION, 2-Hydrazino-1,3-benzothiazole-6-carbohydrazide, ...
Authors:Liu, J.
Deposit date:2016-10-11
Release date:2017-02-22
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network
FEBS J., 284, 2017
5YFG
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SOLUTION STRUCTURE OF HUMAN MOG1
Descriptor:Ran guanine nucleotide release factor
Authors:Hu, Q., Liu, Y., Bao, X., Liu, H.
Deposit date:2017-09-21
Release date:2017-11-01
Last modified:2018-04-11
Method:SOLUTION NMR
Cite:Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation
J Mol Cell Biol, 10, 2018
6JKK
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CRYSTAL STRUCTURE OF BUBR1 KINASE DOMAIN
Descriptor:Mitotic checkpoint control protein kinase BUB1, GLYCEROL, DI(HYDROXYETHYL)ETHER
Authors:Lin, L., Ye, S., Huang, Y., Liu, X., Zhang, R., Yao, X.
Deposit date:2019-03-01
Release date:2019-06-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules.
Cell Res., 29, 2019
6JKM
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CRYSTAL STRUCTURE OF BUBR1 KINASE DOMAIN
Descriptor:Mitotic checkpoint control protein kinase BUB1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lin, L., Ye, S., Huang, Y., Liu, X., Zhang, R., Yao, X.
Deposit date:2019-03-01
Release date:2019-06-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules.
Cell Res., 29, 2019