Author results

5UZ7
  • Download 5uz7
  • View 5uz7
Molmil generated image of 5uz7
VOLTA PHASE PLATE CRYO-ELECTRON MICROSCOPY STRUCTURE OF A CALCITONIN RECEPTOR-HETEROTRIMERIC GS PROTEIN COMPLEX
Descriptor:Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Liang, Y.L., Khoshouei, M., Radjainia, M., Zhang, Y., Glukhova, A., Tarrasch, J., Thal, D.M., Furness, S.G.B., Christopoulos, G., Coudrat, T., Danev, R., Baumeister, W., Miller, L.J., Christopoulos, A., Kobilka, B.K., Wootten, D., Skiniotis, G., Sexton, P.M.
Deposit date:2017-02-24
Release date:2017-05-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
Nature, 546, 2017
6B3J
  • Download 6b3j
  • View 6b3j
Molmil generated image of 6b3j
3.3 ANGSTROM PHASE-PLATE CRYO-EM STRUCTURE OF A BIASED AGONIST-BOUND HUMAN GLP-1 RECEPTOR-GS COMPLEX
Descriptor:Glucagon-like peptide 1 receptor, Exendin-P5, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Liang, Y.L., Khoshouei, M., Glukhova, A., Furness, S.G.B., Koole, C., Zhao, P., Clydesdale, L., Thal, D.M., Radjainia, M., Danev, R., Baumeister, W., Wang, M.W., Miller, L.J., Christopoulos, A., Sexton, P.M., Wootten, D.
Deposit date:2017-09-22
Release date:2018-02-21
Last modified:2018-03-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
Nature, 555, 2018
6E3Y
  • Download 6e3y
  • View 6e3y
Molmil generated image of 6e3y
CRYO-EM STRUCTURE OF THE ACTIVE, GS-PROTEIN COMPLEXED, HUMAN CGRP RECEPTOR
Descriptor:Calcitonin gene-related peptide 1, Nanobody 35, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Liang, Y.L., Khoshouei, M., Deganutti, G., Glukhova, A., Koole, C., Peat, T.S., Radjainia, M., Plitzko, J.M., Baumeister, W., Miller, L.J., Hay, D.L., Christopoulos, A., Reynolds, C.A., Wootten, D., Sexton, P.M.
Deposit date:2018-07-16
Release date:2018-09-19
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor.
Nature, 561, 2018
2X8Q
  • Download 2x8q
  • View 2x8q
Molmil generated image of 2x8q
CRYO-EM 3D MODEL OF THE ICOSAHEDRAL PARTICLE COMPOSED OF ROUS SARCOMA VIRUS CAPSID PROTEIN PENTAMERS
Descriptor:CAPSID PROTEIN P27
Authors:K Hyun, J., Radjainia, M., Kingston, R.L., Mitra, A.K.
Deposit date:2010-03-11
Release date:2010-05-19
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (18.299999 Å)
Cite:Proton-Driven Assembly of the Rous Sarcoma Virus Capsid Protein Results in the Formation of Icosahedral Particles.
J.Biol.Chem., 285, 2010
5T7V
  • Download 5t7v
  • View 5t7v
Molmil generated image of 5t7v
METHICILLIN RESISTANT, LINEZOLID RESISTANT STAPHYLOCOCCUS AUREUS 70S RIBOSOME (DELTA S145 UL3)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Belousoff, M.J., Lithgow, T., Eyal, Z., Yonath, A., Radjainia, M.
Deposit date:2016-09-06
Release date:2017-05-31
Last modified:2018-03-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for Linezolid Binding Site Rearrangement in theStaphylococcus aureusRibosome.
MBio, 8, 2017
4ES8
  • Download 4es8
  • View 4es8
Molmil generated image of 4es8
CRYSTAL STRUCTURE OF THE ADHESIN DOMAIN OF EPF FROM STREPTOCOCCUS PYOGENES IN P212121
Descriptor:Epf, GLYCEROL, ACETATE ION, ...
Authors:Linke, C., Siemens, N., Kreikemeyer, B., Baker, E.N.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The Extracellular Protein Factor Epf from Streptococcus pyogenes Is a Cell Surface Adhesin That Binds to Cells through an N-terminal Domain Containing a Carbohydrate-binding Module.
J.Biol.Chem., 287, 2012
4ES9
  • Download 4es9
  • View 4es9
Molmil generated image of 4es9
CRYSTAL STRUCTURE OF THE ADHESIN DOMAIN OF EPF FROM STREPTOCOCCUS PYOGENES IN P21
Descriptor:Epf
Authors:Linke, C., Siemens, N., Kreikemeyer, B., Baker, E.N.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Extracellular Protein Factor Epf from Streptococcus pyogenes Is a Cell Surface Adhesin That Binds to Cells through an N-terminal Domain Containing a Carbohydrate-binding Module.
J.Biol.Chem., 287, 2012
5J09
  • Download 5j09
  • View 5j09
Molmil generated image of 5j09
CRYSTAL STRUCTURE OF DECAMERIC BFDV CAPSID PROTEIN
Descriptor:Beak and feather disease virus capsid protein
Authors:Sarker, S., Raidal, S., Aragao, D., Forwood, J.K.
Deposit date:2016-03-28
Release date:2016-05-04
Last modified:2016-10-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the assembly and regulation of distinct viral capsid complexes.
Nat Commun, 7, 2016
5J36
  • Download 5j36
  • View 5j36
Molmil generated image of 5j36
CRYSTAL STRUCTURE OF 60-MER BFDV CAPSID PROTEIN
Descriptor:Beak and feather disease virus capsid protein, PHOSPHATE ION
Authors:Sarker, S., Raidal, S., Aragao, D., Forwood, J.K.
Deposit date:2016-03-30
Release date:2016-05-04
Last modified:2016-10-12
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural insights into the assembly and regulation of distinct viral capsid complexes.
Nat Commun, 7, 2016
5J37
  • Download 5j37
  • View 5j37
Molmil generated image of 5j37
CRYSTAL STRUCTURE OF 60-MER BFDV CAPSID PROTEIN IN COMPLEX WITH SINGLE STRANDED DNA
Descriptor:Beak and feather disease virus capsid protein, single stranded DNA, PHOSPHATE ION
Authors:Sarker, S., Raidal, S., Aragao, D., Forwood, J.K.
Deposit date:2016-03-30
Release date:2016-05-04
Last modified:2016-10-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the assembly and regulation of distinct viral capsid complexes.
Nat Commun, 7, 2016
5NI1
  • Download 5ni1
  • View 5ni1
Molmil generated image of 5ni1
CRYOEM STRUCTURE OF HAEMOGLOBIN AT 3.2 A DETERMINED WITH THE VOLTA PHASE PLATE
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Khoshouei, M., Radjainia, M., Bunker, R., Baumeister, W., Danev, R.
Deposit date:2017-03-22
Release date:2017-04-12
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM single particle analysis with the Volta phase plate.
Elife, 5, 2016
4E1P
  • Download 4e1p
  • View 4e1p
Molmil generated image of 4e1p
CRYSTAL STRUCTURE OF THE DIMERIZATION DOMAIN OF LSR2 FROM MYCOBACTERIUM TUBERCULOSIS IN THE P 1 21 1 SPACE GROUP
Descriptor:Protein lsr2
Authors:Summers, E.L., Meindl, K., Uson, I., Arcus, V.L.
Deposit date:2012-03-06
Release date:2012-06-20
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.728 Å)
Cite:The structure of the oligomerization domain of Lsr2 from Mycobacterium tuberculosis reveals a mechanism for chromosome organization and protection.
Plos One, 7, 2012
4E1R
  • Download 4e1r
  • View 4e1r
Molmil generated image of 4e1r
CRYSTAL STRUCTURE OF THE DIMERIZATION DOMAIN OF LSR2 FROM MYCOBACTERIUM TUBERCULOSIS IN THE P 31 2 1 SPACE GROUP
Descriptor:Protein lsr2
Authors:Summers, E.L., Meindl, K., Uson, I., Arcus, V.L.
Deposit date:2012-03-06
Release date:2012-06-20
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.041 Å)
Cite:The structure of the oligomerization domain of Lsr2 from Mycobacterium tuberculosis reveals a mechanism for chromosome organization and protection.
Plos One, 7, 2012
5JCG
  • Download 5jcg
  • View 5jcg
Molmil generated image of 5jcg
STRUCTURE OF HUMAN PEROXIREDOXIN 3 AS THREE STACKED RINGS
Descriptor:Thioredoxin-dependent peroxide reductase, mitochondrial
Authors:Yewdall, N.A., Gerrard, J.A., Goldstone, D.C.
Deposit date:2016-04-15
Release date:2016-05-25
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Human Peroxiredoxin 3 Suggest Self-Chaperoning Assembly that Maintains Catalytic State.
Structure, 24, 2016
5TCU
  • Download 5tcu
  • View 5tcu
Molmil generated image of 5tcu
METHICILLIN SENSITIVE STAPHYLOCOCCUS AUREUS 70S RIBOSOME
Descriptor:16S RRNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Eyal, Z., Ahmed, T., Belousoff, N., Mishra, S., Matzov, D., Bashan, A., Zimmerman, E., Lithgow, T., Bhushan, S., Yonath, A.
Deposit date:2016-09-15
Release date:2017-05-24
Last modified:2017-09-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
MBio, 8, 2017
6CXO
  • Download 6cxo
  • View 6cxo
Molmil generated image of 6cxo
COMPLEMENT COMPONENT-9
Descriptor:Complement component C9, ZINC ION, CALCIUM ION, ...
Authors:Law, R.H.P., Spicer, B.A., Caradoc-Davies, T.T.
Deposit date:2018-04-03
Release date:2018-09-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
6DLW
  • Download 6dlw
  • View 6dlw
Molmil generated image of 6dlw
COMPLEMENT COMPONENT POLYC9
Descriptor:Complement component C9, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Dunstone, M.A., Spicer, B.A., Law, R.H.P.
Deposit date:2018-06-03
Release date:2018-09-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
6U23
  • Download 6u23
  • View 6u23
Molmil generated image of 6u23
EM STRUCTURE OF MPEG-1(W.T.) SOLUBLE PRE-PORE
Descriptor:Macrophage-expressed gene 1 protein, N-ACETYL-D-GLUCOSAMINE
Authors:Pang, S.S., Bayly-Jones, C.
Deposit date:2019-08-19
Release date:2019-09-25
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2J
  • Download 6u2j
  • View 6u2j
Molmil generated image of 6u2j
EM STRUCTURE OF MPEG-1 (L425K, ALPHA CONFORMATION) SOLUBLE PRE-PORE COMPLEX
Descriptor:Macrophage-expressed gene 1 protein, N-ACETYL-D-GLUCOSAMINE
Authors:Pang, S.S., Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (2.37 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2K
  • Download 6u2k
  • View 6u2k
Molmil generated image of 6u2k
EM STRUCTURE OF MPEG-1 (L425K, ALPHA CONFORMATION) SOLUBLE PRE-PORE COMPLEX
Descriptor:Macrophage-expressed gene 1 protein, N-ACETYL-D-GLUCOSAMINE
Authors:Pang, S.S., Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2L
  • Download 6u2l
  • View 6u2l
Molmil generated image of 6u2l
EM STRUCTURE OF MPEG-1 (L425K, BETA CONFORMATION) SOLUBLE PRE-PORE COMPLEX
Descriptor:Macrophage-expressed gene 1 protein, N-ACETYL-D-GLUCOSAMINE
Authors:Pang, S.S., Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2W
  • Download 6u2w
  • View 6u2w
Molmil generated image of 6u2w
EM STRUCTURE OF MPEG-1(L425K) PRE-PORE COMPLEX BOUND TO LIPOSOME
Descriptor:Macrophage-expressed gene 1 protein, N-ACETYL-D-GLUCOSAMINE
Authors:Pang, S.S., Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019